Natural childbirth is a physiological phenomenon of giving birth to a child that is experienced in the lives of most women; however, this experience is accompanied by stress, worry, fear, and pain, and these factors affect the quality of childbirth and the health of the mother and child. Preparing women for natural childbirth in a hospital setting should be accompanied by designing appropriate spaces to properly respond to the physical and psychological needs of mothers. Therefore, the purpose of this research is to assess the needs regarding the requirements of designing hospital spaces to prepare women for natural childbirth in accordance with their physical and psychological needs. The information required in this applied research was collected through documentary and field study methods, and a questionnaire was used as a research tool, and the research was conducted in a descriptive-survey manner. The results of the research include the introduction of design requirements in three categories: structural and furniture-related factors, environmental factors, and palliative-supportive factors, which can be used as a practical framework by designers, architects, and managers of medical centers to improve the mothers' experience as well as have long-term desirable effects on their physical and mental health.